Recently, the analytical instrument industry has made significant progress, injecting new vitality into its development, whether it is the improvement of performance at the enterprise level or the breakthroughs in major national scientific instrument projects.

In terms of enterprise development, the 2024 annual report released by Focus Technology has achieved impressive results. In 2024, the company achieved a total operating revenue of 3.614 billion yuan, a year-on-year increase of 13.58%; The net profit attributable to the parent company reached 207 million yuan, a significant increase of 164.11% year-on-year; The net profit attributable to shareholders was 127 million yuan, a year-on-year increase of 132.82%; Basic earnings per share were 0.46 yuan/share, a year-on-year increase of 163.89%.

From the perspective of business segments, the instrument business achieved a revenue of 2.56 billion yuan, a year-on-year increase of 15.36%; The revenue from related software, consumables, and operational services was 519 million yuan, a year-on-year increase of 18.54%; The revenue from testing services and consulting services/environmental equipment and engineering business reached 426 million yuan, a year-on-year increase of 7.14%. The gross profit margin has also increased, with the company's comprehensive gross profit margin reaching 44.43%, a year-on-year increase of 3.17 percentage points. During the period, the expense ratio significantly decreased, with sales, management, finance, and R&D expense ratios decreasing by 4.43, 2.71, 6.05, and 1.18 percentage points year-on-year, respectively. This is mainly due to the company optimizing its business, products, and personnel configuration, resulting in a year-on-year decrease of 25.75% in research and development expenses. At the same time, the company focuses on core instrument businesses such as scientific instruments, life science instruments, and industrial analytical instruments, and appropriately shrinks some unprofitable businesses.

In terms of breakthroughs in high-end analytical instrument technology, the subsidiary of Focus Technology, Puyu Technology, has performed outstandingly. It continues to improve its product technology platforms such as mass spectrometry, chromatography, spectroscopy, and physical and chemical pretreatment, forming a business model of "multi technology platform multi product combination multi scenario application". Multiple key products have reached international advanced or domestic leading levels through technical appraisal, such as mass spectrometry flow cytometry analyzer, fully automatic intelligent monitoring system for volatile aldehydes and ketones, handheld laser-induced breakdown spectrometer, etc., filling the gap in related fields in China. In the field of mass spectrometry, Spectrum Education Technology has mastered multiple mass spectrometry analysis technology platforms such as ion traps, quadrupole rods, triple quadrupole rods, time-of-flight, and cascade high-resolution, and has achieved a series of high-end mass spectrometry industrialization, achieving good economic and social benefits.

Good news has also been reported in the national major scientific instrument and equipment development special project. The four projects of "Development and Application of Cesium Atomic Fountain Reference Clock", "Development and Application of Cross scale Micro nano Measurement Instrument", "Micro membrane Pump Driven Nucleic Acid Micro Total Analyzer", and "Development and Application Demonstration of Proton Transfer Reaction Mass Spectrometry Instrument" have successfully passed the acceptance inspection.

The project of "Development and Application of Cesium Atomic Fountain Reference Clock" is led by Academician Li Tianchu of the Chinese Academy of Metrology. This project has overcome key technologies such as cold atom preparation, cooling and detection, ultra stable microwave generation, and fiber optic high fidelity transmission of time and frequency. It has successfully developed instruments such as cesium atomic fountain reference clock (NIM6), fiber optic frequency transmission instrument, rubidium fountain standard clock, and rubidium fountain clock engineering prototype. Among them, the frequency uncertainty of NIM6 is better than 5.8E-16, which is equivalent to a difference of no less than 1 second in 54 million years; The fiber optic frequency transmitter can transmit frequency signals with high stability and reliability on fiber optic links ranging from 1 to 100 km; The rubidium fountain standard clock has a frequency accuracy of 1.9E-15 after calibration with the reference clock. These achievements provide important metrological support for the construction of China's time-frequency system and related fields.

The project of "Development and Application of Cross scale Micro nano Measurement Instruments" is led by Shanghai Institute of Metrology and Testing Technology. The project has overcome key technologies such as macro micro linkage multi axis drive and multi probe integration, atomic deposition grating nano value traceability, and dual angle oblique field scanning, and developed six different types of measuring instruments. Its key indicators such as measurement range, nanometer scale grating standard pitch, and vertical scanning range of optical interferometry measurement perform excellently, providing detection support for micro nano standards, precision optical instruments, semiconductors, environmental monitoring, and other fields. It has been widely applied in aerospace, microelectronics, environmental monitoring, and other fields.

The project of "Micro membrane Pump Driven Nucleic Acid Micro Total Analyzer" is jointly undertaken by China Academy of Inspection and Quarantine Sciences, Beijing Bohui Innovation Biotechnology Co., Ltd., and others. The project has overcome key technologies such as the core technology of nucleic acid micro total analysis instruments, microfluidic drive control platform, and integration of high-throughput detection and fluorescence detection units, and developed multifunctional nucleic acid micro total analyzers and portable nucleic acid micro total analyzers. In response to the needs of environmental monitoring, biometric, inspection and quarantine, disease diagnosis and research, and other fields, multiple analytical technology bottlenecks have been solved. The detection sensitivity is one order of magnitude higher than conventional PCR, and the detection time is 1/5 of conventional PCR methods. At the same time, the first automated production line for microfluidic chips in China has been built, and related instruments and supporting reagents have been registered and certified for sale.

The project of "Development and Application Demonstration of Proton Transfer Reaction Mass Spectrometry Instrument" is jointly undertaken by Beijing Institute of Metrology and Testing Science, Beijing Kaier Technology Development Co., Ltd., and others. The project aims to meet the needs of rapid tracking of atmospheric haze pollution sources, monitoring of toxic and harmful gases in manned spacecraft enclosed cabins, and terrorist attacks of chemical agents in public places. Key technologies such as high-precision proton transfer ion sources, dual field acceleration and no net reflection in time-of-flight mass spectrometry, wide dynamic range signal acquisition and extraction and fast online digital filtering in quadrupole mass spectrometry, and development of high-precision mass spectrometry evaluation standard gases have been overcome. The project has successfully developed proton transfer reaction time-of-flight mass spectrometer (PTR-TOFMS) and quadrupole proton transfer reaction mass spectrometer (PTR-QMS), which can achieve real-time, rapid, and high-sensitivity detection of multi-component volatile organic compounds. The key technical indicators have reached the level of similar international instruments and have been applied in areas such as atmospheric haze monitoring and environmental monitoring in enclosed cabins. Demonstration.

These advances in the analytical instrument industry not only demonstrate the strength improvement of enterprises in market competition, but also reflect the breakthrough achievements of the country in the research and development of major scientific instruments, which will further promote technological progress and industrial development in related fields, and provide stronger technical support for multiple fields such as scientific research, industrial production, and environmental monitoring.